Journal of Hepatology
Volume 33, Issue 3 , Pages 348-351 , September 2000

Association of human liver bilirubin UDP-glucuronyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene

  • Maarten T.M Raijmakers

      Affiliations

    • Department of GastroenterologyThe Netherlands
    • ,
  • Peter L.M Jansen

      Affiliations

    • Department of Gastroenterology, University Hospital Groningen, The Netherlands
    • ,
  • Eric A.P Steegers

      Affiliations

    • Obstetrics and Gynaecology, University Hospital St. Radboud, Nijmegen,The Netherlands
    • ,
  • Wilbert H.M Peters

      Affiliations

    • Corresponding Author InformationWilbert H. M. Peters, Department of Gastroenterology, University Hospital St. Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Tel: 31 24 3615123. Fax: 31 24 3540103.
    • Department of GastroenterologyThe Netherlands

Received 13 August 1999 ,Revised 2 December 1999 ,Accepted 10 January 2000.

References 

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  2. Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, et al.  The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med. 1995;333:1171–1175
  3. Monaghan G, Ryan M, Seddon R, Hume R, Burchell B. Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome. Lancet. 1996;347:578–581
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  15. Galanello R, Perseu L, Cipollina ML, Barella S, Giagu N, Turco MP, et al.  Hyperbilirubinaemia in heterozygous β-thalassaemia is related to co-inherited Gilbert's syndrome. Br J Haematol. 1997;99:433–436
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PII: S0168-8278(00)80268-8

Journal of Hepatology
Volume 33, Issue 3 , Pages 348-351 , September 2000

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