Journal of Hepatology
Volume 39, Issue 2 , Pages 193-199 , August 2003

Vasopressin accelerates experimental ammonia-induced brain edema in rats after portacaval anastomosis

Received 2 November 2002 ,Revised 18 March 2003 ,Accepted 1 April 2003.

References 

  1. Jalan R, Olde Damink SW, Deutz NE, Hayes PC, Lee A. Restoration of cerebral blood flow autoregulation and reactivity to CO2 in acute liver failure by moderate hypothermia. Hepatology. 2001;34:50–54
  2. Strauss G, Hansen BA, Knudsen GM, Larsen FS. Hyperventilation restores cerebral blood flow autoregulation in patients with acute liver failure. J Hepatol. 1998;28:199–203
  3. Clemmesen JO, Hansen BA, Larsen FS. Indomethacin normalizes intracranial pressure in acute liver failure: a twenty-three-year-old woman treated with indomethacin. Hepatology. 1997;26:1423–1425
  4. Blei AT, Larsen FS. Pathophysiology of cerebral edema in fulminant hepatic failure. J Hepatol. 1999;31:771–776
  5. Aggarwal S, Kramer D, Yonas H, Obrist W, Kang Y, Martin M, et al.  Cerebral hemodynamic and metabolic changes in fulminant hepatic failure: a retrospective study. Hepatology. 1994;19:80–87
  6. Larsen FS. Cerebral circulation in liver failure: Ohm's law in force. Semin Liver Dis. 1996;16:281–292
  7. Master S, Gottstein J, Blei AT. Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis. Hepatology. 1999;30:876–880
  8. Cordoba J, Crespin J, Gottstein J, Blei AT. Mild hypothermia modifies ammonia-induced brain edema in rats after portacaval anastomosis. Gastroenterology. 1999;116:686–693
  9. Chung C, Gottstein J, Blei AT. Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis. Hepatology. 2001;34:249–254
  10. Suzuki Y, Satoh S, Oyama H, Takayasu M, Shibuya M. Regional differences in the vasodilator response to vasopressin in canine cerebral arteries in vivo. Stroke. 1993;24:1049–1053 (discussion p. 1053–4)
  11. Takayasu M, Kajita Y, Suzuki Y, Shibuya M, Sugita K, Ishikawa T, et al.  Triphasic response of rat intracerebral arterioles to increasing concentrations of vasopressin in vitro. J Cereb Blood Flow Metab. 1993;13:304–309
  12. Kozniewska E, Szczepanska-Sadowska E. V2-like receptors mediate cerebral blood flow increase following vasopressin administration in rats. J Cardiovasc Pharmacol. 1990;15:579–585
  13. Wenzel V, Lindner KH, Krismer AC, Voelckel WG, Schocke MF, Hund W, et al.  Survival with full neurologic recovery and no cerebral pathology after prolonged cardiopulmonary resuscitation with vasopressin in pigs. J Am Coll Cardiol. 2000;35:527–533
  14. Wenzel V, Lindner KH. Arginine vasopressin during cardiopulmonary resuscitation: laboratory evidence, clinical experience and recommendations, and a view to the future. Crit Care Med. 2002;30(4 Suppl):S157–S161
  15. Traber P, DalCanto M, Ganger D, Blei AT. Effect of body temperature on brain edema and encephalopathy in the rat after hepatic devascularization. Gastroenterology. 1989;96:885–891
  16. Manning M, Przybylski JP, Olma A, Klis WA, Kruszynski M, Wo NC, et al.  No requirements of cyclic conformation of antagonists in binding to vasopressin receptors. Nature. 1987;329:839–840
  17. Larsen FS, Ejlersen E, Hansen BA, Knudsen GM, Tygstrup N, Secher NH. Functional loss of cerebral blood flow autoregulation in patients with fulminant hepatic failure. J Hepatol. 1995;23:212–217
  18. Olpe HR, Steinmann M. Responses of locus coeruleus neurons to neuropeptides. Prog Brain Res. 1991;88:241–248
  19. Wendon JA, Harrison PM, Keays R, Williams R. Cerebral blood flow and metabolism in fulminant liver failure. Hepatology. 1994;19:1407–1413
  20. Niermann H, Amiry-Moghaddam M, Holthoff K, Witte OW, Ottersen OP. A novel role of vasopressin in the brain: modulation of activity-dependent water flux in the neocortex. J Neurosci. 2001;21:3045–3051
  21. Sarfaraz D, Fraser CL. Effects of arginine vasopressin on cell volume regulation in brain astrocyte in culture. Am J Physiol. 1999;276:E596–E601
  22. Faraci FM, Mayhan WG, Schmid PG, Heistad DD. Effects of arginine vasopressin on cerebral microvascular pressure. Am J Physiol. 1988;255:H70–H76
  23. Prengel AW, Lindner KH, Keller A. Cerebral oxygenation during cardiopulmonary resuscitation with epinephrine and vasopressin in pigs. Stroke. 1996;27:1241–1248
  24. Guevara M, Bru C, Gines P, Fernandez-Esparrach G, Sort P, Bataller R, et al.  Increased cerebrovascular resistance in cirrhotic patients with ascites. Hepatology. 1998;28:39–44
  25. Lockwood AH, Yap EW, Wong WH. Cerebral ammonia metabolism in patients with severe liver disease and minimal hepatic encephalopathy. J Cereb Blood Flow Metab. 1991;11:337–341
  26. Strauss GI, Knudsen GM, Kondrup J, Moller K, Larsen FS. Cerebral metabolism of ammonia and amino acids in patients with fulminant hepatic failure. Gastroenterology. 2001;121:1109–1119

PII: S0168-8278(03)00185-5

doi: 10.1016/S0168-8278(03)00185-5

Journal of Hepatology
Volume 39, Issue 2 , Pages 193-199 , August 2003