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Journal of Hepatology
Volume 42, Issue 1
, Pages 75-81
, January 2005
The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARγ. Influence of albumin
References
- . Cyclooxygenase 2 inhibitors: discovery, selectivity and the future. Trends Pharmacol Sci. 1999;20:465–469
- . Cox-2 inhibitors: today and tomorrow. Am J Med Sci. 2002;323:181–189
- . Prostaglandins and other cyclooxygenase-dependent arachidonic acid metabolites and the kidney in liver disease. Prostaglandins Other Lipid Mediat. 2003;72:19–33
- Selective inhibition of cyclooxygenase 2 spares renal function and prostaglandin synthesis in cirrhotic rats with ascites. Gastroenterology. 1999;116:1167–1175
- Cyclooxygenase-1 derived prostaglandins are involved in the maintenance of renal function in rats with cirrhosis and ascites. Br J Pharmacol. 2002;135:891–900
- Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB. FASEB J. 2001;15:1622–1624
- . The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. J Biol Chem. 2000;275:11397–11403
- . Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. FEBS Lett. 2002;531:278–284
- Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med. 1999;5:1418–1423
- . Celecoxib activates a novel mitochondrial apoptosis signaling pathway. FASEB J. 2003;17:1547–1549
- Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4. FASEB J. 2002;16:1937–1939
- . Anatomy of the kidney. In: Brenner BM, Rector FC editor. The kidney. Philadelphia, PA: WB Saunders Company; 1991;p. 3–75
- . Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science. 1987;237:1171–1176
- Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. J Clin Invest. 1992;90:136–141
- Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin. Biochem Pharmacol. 2001;62:1587–1595
- . Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs. J Biol Chem. 1997;272:3406–3410
- . Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. J Pharmacol Exp Ther. 2002;302:18–25
- . Pathophysiology of progressive nephropathies. N Engl J Med. 1998;339:1448–1456
- . Serum albumin. Adv Protein Chem. 1985;37:161–245
- . Human physiology and mechanisms of disease. Philadelphia, PA: WB Saunders Company; 1997;
- . Albumin-lipid interactions: prostaglandin stability as a probe for characterizing binding sites on vertebrate albumins. Biochemistry. 1981;20:6129–6134
- Serum albumin is a specific inhibitor of apoptosis in human endothelial cells. J Cell Sci. 1996;109:2571–2580
- . pH-Dependent regulation of leukocyte 5-lipoxygenase activity in inflammatory exudates by albumin. Inflamm Res. 1997;46:366–372
- . Albumin redirects platelet eicosanoid metabolism toward 12(S)-hydroxyeicosatetraenoic acid. J Lipid Res. 1989;30:1925–1932
- . Albumin prevents metabolism of 12-hydroxyeicosatetraenoic acid by leukocytes in vitro. Biochim Biophys Acta. 1996;1303:154–160
- . Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid. Biochim Biophys Acta. 1997;1346:75–85
- . Albumin modifies the metabolism of hydroxyeicosatetraenoic acids via 12-lipoxygenase in human platelets. J Lipid Res. 1999;40:940–947
- Randomized trial comparing albumin, dextran 70, and polygeline in cirrhotic patients with ascites treated by paracentesis. Gastroenterology. 1996;111:1002–1010
- Effect of intravenous albumin on renal impairment and mortality in patients with cirrhosis and spontaneous bacterial peritonitis. N Engl J Med. 1999;341:403–409
- . Cyclosporin A suppresses proliferation of renal mesangial cells in culture. Biochem Pharmacol. 1988;37:1083–1088
- . Interleukin-1-induced cyclooxygenase 2 expression is suppressed by cyclosporin A in rat mesangial cells. Kidney Int. 1994;45:150–158
- . 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell. 1995;83:803–812
- . Leukotrienes and other lipoxygenase products of arachidonic-acid synthesized in the kidney. Am J Med. 1986;81:12–22
- . A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA. 1990;87:9383–9387
- . Generation of 8-epiprostaglandin F2alpha by human monocytes. Discriminate production by reactive oxygen species and prostaglandin endoperoxide synthase-2. J Biol Chem. 1996;271:8919–8924
- Selective COX-2 inhibition improves endothelial function in coronary artery disease. Circulation. 2003;107:405–409
- . Cheminformatic models to predict binding affinities to human serum albumin. J Med Chem. 2001;44:4370–4378
- . Clinical pharmacokinetics and pharmacodynamics of celecoxib. A selective cyclo-oxygenase-2 inhibitor. Clin Pharmacokinet. 2000;38:225–242
- . Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro. J Biol Chem. 1983;258:11713–11718
- . Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12–14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo. Endocrinology. 2001;142:551–556
- . Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors. Arthritis Rheum. 2002;46:3159–3167
- Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. J Lipid Mediat. 1993;6:417–420
- . Effects of 12-HETE on isolated dog renal arcuate arteries. Am J Physiol. 1991;261:H451–H456
- . Urinary thromboxane-B2 and prostaglandin-E2 in the hepatorenal-syndrome. Evidence for increased vasoconstrictor and decreased vasodilator factors. Gastroenterology. 1983;84:697–703
- Effects of celecoxib and naproxen on renal function in patients with cirrhosis and ascites: a double-blind randomized controlled trial. J Hepatol. 2004;40:3–4
☆ The authors state that they did not receive funding from the drug manufacturers of the study. However, they state that one author, Jaime L. Masferrer, is an employee of the company.
PII: S0168-8278(04)00433-7
doi: 10.1016/j.jhep.2004.09.011
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Journal of Hepatology
Volume 42, Issue 1
, Pages 75-81
, January 2005
