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Journal of Hepatology
Volume 47, Issue 4
, Pages 451-453
, October 2007
NASH and thiazolidinediones: Not to be taken lightly
References
- A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 2006;355:2297–2307
- Pioglitazone treatment increases whole body fat but not total body water in patients with non-alcoholic steatohepatitis. J Hepatol. 2007;47:565–570
- Survival, liver failure, and hepatocellular carcinoma in obesity-related cryptogenic cirrhosis. Hepatology. 2002;35:1485–1493
- Kim M, Wands J. Insulin pathway. In: Dufour J-F, Clavien PA, editors. Signaling pathways in liver diseases, 2005. p. 105–13.
- . Inflammation and metabolic disorders. Nature. 2006;444:860–867
- Genolet R, Michalik L, Wahli W. PPARs. In: Dufour J-F, Clavien PA, editors. Signaling pathways in liver dieases, 2005. p. 267–280.
- . A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis. Am J Gastroenterol. 2001;96:519–525
- . Improved nonalcoholic steatohepatitis after 48
weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology. 2003;38:1008–1017 - A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology. 2004;39:188–196
- A one year randomized, placebo-controlled, double blind trial of rosiglitazone in non-alcoholic steatohepatitis: results of the FLIRT pilot trial. J Hepatol. 2006;44:S272
- Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003. Circulation. 2003;108:2941–2948
- Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease. World J Gastroenterol. 2006;12:5813–5819
- Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab. 2002;87:2784–2791
- . Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356:2457–2471
- Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial. Lancet. 2006;368:1096–1105
- Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med. 2006;355:2427–2443
- . The record on rosiglitazone and the risk of myocardial infarction. N Engl J Med. 2007;357:67–69
- Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet. 2005;366:1279–1289
- Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology. 2006;44:865–873
- An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitus. Metabolism. 2007;56:332–338
- Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006;313:1137–1140
- Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial. Hepatology. 2004;39:770–778
- Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin E in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2006;4:1537–1543
☆ The author declares that he has a relationship with the manufacturers, of rosiglitazone Avandia®. He is the principle investigator of an investigation-initiated study testing rosiglitazone in NASH. Furthermore, he declares he received funding from GlaxoSmithKline to carry out his study.
PII: S0168-8278(07)00408-4
doi: 10.1016/j.jhep.2007.07.012
© 2007 European Association for the Study of the Liver. Published by Elsevier Inc. All rights reserved.
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Journal of Hepatology
Volume 47, Issue 4
, Pages 451-453
, October 2007
