Journal of Hepatology
Volume 48, Issue 1 , Pages 61-67 , January 2008

Presence of bacterial-DNA in cirrhosis identifies a subgroup of patients with marked inflammatory response not related to endotoxin

  • José M. González-Navajas

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Unidad Hepática, Hospital General Universitario, Alicante, Spain
    • ,
  • Pablo Bellot

      Affiliations

    • Sección de Immunología, Hospital General Universitario, Alicante, Spain
    • ,
  • Rubén Francés

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Unidad Hepática, Hospital General Universitario, Alicante, Spain
    • ,
  • Pedro Zapater

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Laboratorio de Hemodinámica Hepática, Hospital Clínic, IDIBAPS, Barcelona, Spain
    • ,
  • Carlos Muñoz

      Affiliations

    • Servicio de Farmacología Clínica, Hospital General Universitario, Alicante, Spain
    • ,
  • Juan Carlos García-Pagán

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Sección de Immunología, Hospital General Universitario, Alicante, Spain
    • ,
  • Sonia Pascual

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Unidad Hepática, Hospital General Universitario, Alicante, Spain
    • ,
  • Miguel Pérez-Mateo

      Affiliations

    • Unidad Hepática, Hospital General Universitario, Alicante, Spain
    • ,
  • Jaime Bosch

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Unidad Hepática, Hospital Clínic, IDIBAPS, Barcelona, Spain
    • ,
  • José Such

      Affiliations

    • CIBERehd, Instituto de Salud Carlos III, Madrid, Spain
    • Unidad Hepática, Hospital General Universitario, Alicante, Spain
    • Corresponding Author InformationCorresponding author. Tel./fax: +34 965 938 345.

Received 31 May 2007 ,Revised 27 August 2007 ,Accepted 29 August 2007.

References 

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  4. Such J, Frances R, Munoz C, Zapater P, Casellas JA, Cifuentes A, et al. Detection and identification of bacterial DNA in patients with cirrhosis and culture-negative, nonneutrocytic ascites. Hepatology. 2002;36:135–141
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☆ The authors declare that they do not have anything to disclose regarding conflict of interest with respect to this manuscript.

PII: S0168-8278(07)00559-4

doi: 10.1016/j.jhep.2007.08.012

Journal of Hepatology
Volume 48, Issue 1 , Pages 61-67 , January 2008

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