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Journal of Hepatology
Volume 49, Issue 2
, Pages 299-300
, August 2008
Perspectives for the utilization of neutralizing human monoclonal antibodies as anti-HCV drugs
References
- Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nat Med. 2008;14:25–27
- Diverging effects of human recombinant anti-hepatitis C virus (HCV) antibody fragments derived from a single patient on the infectivity of a vesicular stomatitis virus/HCV pseudotype. J Virol. 2002;76:11775–11779
- Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection. J Virol. 2005;79:6023–6034
- Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C. Proc Natl Acad Sci USA. 2007;104:6025–6030
- Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma. Nat Med. 1999;5:211–216
- . Therapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies. Curr Top Microbiol Immunol. 2008;317:1–38
- Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein. J Virol. 2008;82:1047–1052
- . Is reduction of viral fitness a valid antiviral approach?. Drug Discov Today: Ther Strategies. 2008;
☆ The authors declare that they do not have anything to disclose regarding funding from industries or conflict of interest with respect to this manuscript.
PII: S0168-8278(08)00316-4
doi: 10.1016/j.jhep.2008.05.008
© 2008 European Association for the Study of the Liver. Published by Elsevier Inc. All rights reserved.
« Previous
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Journal of Hepatology
Volume 49, Issue 2
, Pages 299-300
, August 2008
