Journal of Hepatology
Volume 49, Issue 4 , Pages 548-556, October 2008

DNA polymorphisms and response to treatment in patients with chronic hepatitis C: Results from the HALT-C trial☆☆

  • Timothy R. Morgan

      Affiliations

    • Division of Gastroenterology, University of California-Irvine, Irvine, CA, USA
    • Gastroenterology Service, VA Long Beach Healthcare System, Long Beach, CA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 562 826 5756; fax: +1 562 826 5436.
  • ,
  • Richard W. Lambrecht

      Affiliations

    • Department of Medicine and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, USA
  • ,
  • Herbert L. Bonkovsky

      Affiliations

    • Department of Medicine and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, USA
    • Department of Molecular and Structural Biology and The Liver-Biliary-Pancreatic Center, University of Connecticut Health Center, Farmington, CT, USA
    • Carolinas Medical Center, Charlotte, NC, USA
  • ,
  • Raymond T. Chung

      Affiliations

    • Gastrointestinal Unit, Medical Services, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston, MA, USA
  • ,
  • Deepa Naishadham

      Affiliations

    • New England Research Institutes, Watertown, MA, USA
  • ,
  • Richard K. Sterling

      Affiliations

    • Hepatology Section, Virginia Commonwealth University Medical Center, Richmond, VA, USA
  • ,
  • Robert J. Fontana

      Affiliations

    • Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA
  • ,
  • William M. Lee

      Affiliations

    • Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA
  • ,
  • Marc G. Ghany

      Affiliations

    • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
  • ,
  • Elizabeth C. Wright

      Affiliations

    • Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
  • ,
  • Thomas R. O’Brien

      Affiliations

    • Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
  • ,
  • the HALT-C Trial Group

Received 20 December 2007; received in revised form 4 May 2008; accepted 8 May 2008. published online 05 June 2008.

Associate Editor: C.P. Day

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 Financial relationships of the authors with Hoffmann-La Roche, Inc., are as follows: T.R. Morgan is a consultant, is on the speaker’s bureau and receives research support; R.T. Chung receives research support; R.K. Sterling is a consultant, on the speaker’s bureau, and receives research support; R.J. Fontana is on the speaker’s bureau; and W.M. Lee receives research support. Authors with no financial relationships related to this project are: R.W. Lambrecht, H.L. Bonkovsky, D. Naishadham, M.G. Ghany, E.C. Wright, and T.R. O’Brien. This is a NIH funded study.

☆☆ This is publication number 30 from the HALT-C Trial Group.

PII: S0168-8278(08)00354-1

doi:10.1016/j.jhep.2008.05.011

Journal of Hepatology
Volume 49, Issue 4 , Pages 548-556, October 2008