Journal of Hepatology
Volume 49, Issue 5 , Pages 686-687 , November 2008

Branched-chain amino acids antagonism in patients with cirrhosis and a simulated upper GI bleed

References 

  1. Khanna S, Gopalan S. Role of branched-chain amino acids in liver disease: the evidence for and against. Curr Opin Clin Nutr Metab Care. 2007;10:297–303
  2. Espinal J, Beggs M, Patel H, Randle PJ. Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart. Biochem J. 1986;237:285–288
  3. Olde Damink SW, Jalan R, Deutz NE, Dejong CH, Redhead DN, Hynd P, et al. Isoleucine infusion during simulated upper gastrointestinal bleeding improves liver and muscle protein synthesis in cirrhotic patients. Hepatology. 2007;45:560–568
  4. Olde Damink SWM, Jalan R, Deutz NEP, Hayes PC, Soeters PB. Protein synthesis is severely diminished following a simulated upper GI bleed in patients with cirrhosis. J Hepatol. 2008;49:726–731
  5. Harper AE, Benton DA, Winje M, Elvehjem CA. Leucine and isoleucine antagonism in rat. Arch Biochem Biophys. 1954;51:523–524

☆ The author declares that he does not have anything to disclose regarding funding from industries or conflict of interest with respect to this manuscript.

PII: S0168-8278(08)00502-3

doi: 10.1016/j.jhep.2008.08.005

Journal of Hepatology
Volume 49, Issue 5 , Pages 686-687 , November 2008

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