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Journal of Hepatology
Volume 49, Issue 6
, Pages 1038-1045
, December 2008
Genetic factors of susceptibility and of severity in primary biliary cirrhosis
References
- . Genetics and geoepidemiology of primary biliary cirrhosis: following the footprints to disease etiology. Semin Liver Dis. 2005;25:265–280
- . Genetic factors in the pathogenesis of primary biliary cirrhosis. Clin Liver Dis. 2003;7:841–864
- . Genes and (auto)immunity in primary biliary cirrhosis. Genes Immun. 2005;6:543–556
- . Genomics and complex liver disease: challenges and opportunities. Hepatology. 2006;44:1380–1390
- HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: a large-scale study. Hepatology. 2006;44:667–674
- CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. J Hepatol. 2000;32:538–541
- Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature. 2003;423:506–511
- . CTLA-4 and its role in autoimmune thyroid disease. J Mol Endocrinol. 2003;31:21–36
- . Autoimmunity in systemic lupus erythematosus: integrating genes and biology. Semin Immunol. 2006;18:230–243
- Association of CTLA4 single nucleotide polymorphisms with viral but not autoimmune liver disease. Eur J Gastroenterol Hepatol. 2007;19:947–951
- . Interacting alleles of the coinhibitory immunoreceptor genes cytotoxic T-lymphocyte antigen 4 and programmed cell-death 1 influence risk and features of primary biliary cirrhosis. Hepatology. 2008;47:563–570
- . Treatment of primary biliary cirrhosis. Baillieres Best Pract Res Clin Gastroenterol. 2000;14:615–628
- . Primary biliary cirrhosis. N Engl J Med. 2005;353:1261–1273
- . Automated identification of single nucleotide polymorphisms from sequencing data. J Bioinform Comput Biol. 2003;1:253–265
- An integrated system for high throughput TaqMan based SNP genotyping. Bioinformatics. 2001;17:654–655
- . Model-free analysis and permutation tests for allelic associations. Hum Hered. 2000;50:133–139
- . Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol. 2001;19:225–252
- The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum Mol Genet. 1996;5:1075–1080
- . A native soluble form of CTLA-4. Cell Immunol. 2000;201:144–153
- Cytotoxic T lymphocyte associated antigen-4 gene polymorphisms confer susceptibility to primary biliary cirrhosis and autoimmune hepatitis in Chinese population. World J Gastroenterol. 2004;10:3056–3059
- Analysis of major histocompatibility complex and CTLA-4 alleles in Brazilian patients with primary biliary cirrhosis. J Gastroenterol Hepatol. 2003;18:1061–1066
- Cytotoxic T-lymphocyte-associated antigen-4 single nucleotide polymorphisms and haplotypes in primary biliary cirrhosis. Clin Gastroenterol Hepatol. 2007;5:755–760
- Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism. Hum Immunol. 2004;65:622–631
- . Autoimmunity and tuberculosis. Opposite association with TNF polymorphism. J Rheumatol. 2005;32:219–224
- Association of the tumour necrosis factor alpha -308 but not the interleukin 10 -627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis. Gut. 2001;49:288–294
- . Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region. J Hepatol. 1999;31:242–247
- Tumour necrosis factor-alpha promoter polymorphisms in primary biliary cirrhosis. J Hepatol. 1999;30:232–236
- The tumor necrosis factor-alpha promoter correlates with progression of primary biliary cirrhosis. J Hepatol. 1999;30:826–829
- . TNF gene polymorphisms in primary biliary cirrhosis: a critical appraisal. J Hepatol. 1999;31:366–368
- . HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility. Gut. 2001;48:397–402
- . Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol. 2005;204:216–237
- . Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol Rev. 2006;86:1179–1236
- . Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice. Biochemistry. 2005;44:12598–12605
- Genetic polymorphisms influencing xenobiotic metabolism and transport in patients with primary biliary cirrhosis. Hepatology. 2005;41:55–63
- . Smoking and increased severity of hepatic fibrosis in primary biliary cirrhosis: a cross validated retrospective assessment. Hepatology. 2006;44:1564–1571
- Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients. Hepatology. 2005;42:1194–1202
- Polymorphisms in the steroid and xenobiotic receptor gene influence survival in primary sclerosing cholangitis. Gastroenterology. 2006;131:781–787
- Bicarbonate-rich choleresis induced by secretin in normal rat is taurocholate-dependent and involves AE2 anion exchanger. Hepatology. 2006;43:266–275
- . The effects of extracellular pH on immune function. J Leukoc Biol. 2001;69:522–530
- . Abnormal expression of anion exchanger genes in primary biliary cirrhosis. Gastroenterology. 1993;105:572–578
- . Decreased anion exchanger 2 immunoreactivity in the liver of patients with primary biliary cirrhosis. Hepatology. 1997;25:12–17
- . Assessment of biliary bicarbonate secretion in humans by positron emission tomography. Gastroenterology. 1999;117:167–172
- Ae2_a,b deficient mice develop antimitochondrial antibodies and other features resembling primary biliary cirrhosis. Gastroenterology. 2008;134:1482–1493
☆ The authors who have taken part in the research of this paper declared that they do not have a relationship with the manufacturers of the materials involved either in the past or present and they did not receive funding from the manufacturers to carry out their research.
PII: S0168-8278(08)00602-8
doi: 10.1016/j.jhep.2008.07.027
© 2008 European Association for the Study of the Liver. Published by Elsevier Inc. All rights reserved.
« Previous
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Journal of Hepatology
Volume 49, Issue 6
, Pages 1038-1045
, December 2008
