Journal of Hepatology
Volume 50, Issue 2 , Pages 394-401, February 2009

Pro-hepcidin is unable to degrade the iron exporter ferroportin unless maturated by a furin-dependent process☆☆☆

  • Bruno Gagliardo

      Affiliations

    • Université Paris Descartes, CNRS (UMR 8601), Paris, France
    • These authors contributed equally to this work.
    • ,
  • Nicole Kubat

      Affiliations

    • Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
    • Inserm, U567, Paris, France
    • These authors contributed equally to this work.
    • ,
  • Audrey Faye

      Affiliations

    • Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
    • Inserm, U567, Paris, France
    • ,
  • Maryse Jaouen

      Affiliations

    • Université Paris Descartes, CNRS (UMR 8601), Paris, France
    • ,
  • Béatrice Durel

      Affiliations

    • Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
    • Inserm, U567, Paris, France
    • ,
  • Jean-Christophe Deschemin

      Affiliations

    • Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
    • Inserm, U567, Paris, France
    • ,
  • François Canonne-Hergaux

      Affiliations

    • CNRS, Institut de Chimie des Substances Naturelles, Gif-Sur-Yvette, France
    • ,
  • Marie-Agnès Sari

      Affiliations

    • Université Paris Descartes, CNRS (UMR 8601), Paris, France
    • ,
  • Sophie Vaulont

      Affiliations

    • Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France
    • Inserm, U567, Paris, France
    • Département de Génétique, Développement et Pathologie Moléculaire, Institut Cochin, Faculté de Médecine Cochin-Port Royal, 24, rue du Fg St Jacques, 75014 Paris, France
    • Corresponding Author InformationCorresponding author. Tel.: +33 1 44412408; fax: +33 1 44412421.

Received 8 August 2008; received in revised form 11 September 2008; accepted 15 September 2008. published online 03 December 2008.

Associate Editor: Y.M. Deugnier

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☆ The authors who have taken part in the research of this paper declared that they do not have a relationship with the manufacturers of the materials involved either in the past or present and they did not receive funding from the manufacturers to carry out their research.

☆☆ Financial support: This work was supported by ANR, Institut National de la Santé et de la Recherche Médicale and CNRS.

PII: S0168-8278(08)00716-2

doi:10.1016/j.jhep.2008.09.018

Journal of Hepatology
Volume 50, Issue 2 , Pages 394-401, February 2009

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