Journal of Hepatology
Volume 50, Issue 4 , Pages 674-683 , April 2009

Entecavir shows limited efficacy in HBeAg-positive hepatitis B patients with a partial virologic response to adefovir therapy

  • Jurriën G.P. Reijnders

      Affiliations

    • Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, ’s Gravendijkwal 230, Room Ha 204, 3015 CE Rotterdam, The Netherlands
  • ,
  • Suzan D. Pas

      Affiliations

    • Department of Virology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
  • ,
  • Martin Schutten

      Affiliations

    • Department of Virology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
  • ,
  • Robert A. de Man

      Affiliations

    • Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, ’s Gravendijkwal 230, Room Ha 204, 3015 CE Rotterdam, The Netherlands
  • ,
  • Harry L.A. Janssen

      Affiliations

    • Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, ’s Gravendijkwal 230, Room Ha 204, 3015 CE Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 (0) 10 703 5942; fax: +31 (0) 10 436 5916.

Received 11 June 2008 ,Revised 8 October 2008 ,Accepted 22 October 2008.

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 H.L.A. Janssen received grants from and is consultant for: Bristol Myers Squibb, Gilead, Novartis, Roche and Schering-Plough. R.A. de Man received an unrestricted research grant from Biotest, clinical trial support from Bristol Myers Squibb and Gilead, and is a member of the Data safety monitoring board of Novartis. The other authors have nothing to declare.

PII: S0168-8278(08)00804-0

doi: 10.1016/j.jhep.2008.10.033

Journal of Hepatology
Volume 50, Issue 4 , Pages 674-683 , April 2009