Journal of Hepatology
Volume 51, Issue 4 , Pages 647-654 , October 2009

Prevalence, viral replication efficiency and antiviral drug susceptibility of rtQ215 polymerase mutations within the hepatitis B virus genome

  • Samad Amini-Bavil-Olyaee

      Affiliations

    • Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany
    • These authors contributed equally to this work.
  • ,
  • Ulf Herbers

      Affiliations

    • Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany
    • These authors contributed equally to this work.
  • ,
  • Seyed Reza Mohebbi

      Affiliations

    • Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
    • Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  • ,
  • Farzaneh Sabahi

      Affiliations

    • Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
  • ,
  • Mohammad Reza Zali

      Affiliations

    • Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • ,
  • Tom Luedde

      Affiliations

    • Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany
  • ,
  • Christian Trautwein

      Affiliations

    • Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany
  • ,
  • Frank Tacke

      Affiliations

    • Department of Medicine III, RWTH-University Hospital Aachen, Pauwelsstraße 30, 52074 Aachen, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 241 8035848; fax: +49 241 8082455.

Received 13 February 2009 ,Revised 22 April 2009 ,Accepted 27 April 2009.

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 C.T. and F.T. have received research grants from Novartis and Bristol-Myers Squibb. The other authors who have taken part in this study declared that they do not have anything to disclose with respect to this manuscript.

PII: S0168-8278(09)00374-2

doi: 10.1016/j.jhep.2009.04.022

Journal of Hepatology
Volume 51, Issue 4 , Pages 647-654 , October 2009