Journal of Hepatology
Volume 51, Issue 3 , Pages 426-429 , September 2009

Infection and inflammation in liver failure: Two sides of the same coin

  • Raza Malik

      Affiliations

    • Liver Failure Group, Institute of Hepatology, University College London and Hospitals, 69-75 Chenies Mews, London WC1E 6HX, UK
    • Beth Israel Deaconess Medical Center; Harvard Medical School, Boston, MA, USA
    • ,
  • Rajeshwar P. Mookerjee

      Affiliations

    • Liver Failure Group, Institute of Hepatology, University College London and Hospitals, 69-75 Chenies Mews, London WC1E 6HX, UK
    • ,
  • Rajiv Jalan

      Affiliations

    • Liver Failure Group, Institute of Hepatology, University College London and Hospitals, 69-75 Chenies Mews, London WC1E 6HX, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 207 6796552.

  • Image Result

    This figure illustrates the possible outcomes of a patient with cirrhosis who is admitted to the hospital depending upon the occurrence and/or resolution of a systemic inflammatory response. In the pa

    This figure illustrates the possible outcomes of a patient with cirrhosis who is admitted to the hospital depending upon the occurrence and/or resolution of a systemic inflammatory response. In the patients in whom the systemic inflammatory response persists, it is likely they will progress to the organ injury/immune dysfunction pathway leading to a high probability of developing acute on chronic liver failure with a self-perpetuating vicious cycle. [This figure appears in colour on the web.]

☆ The authors who have taken part in this study declared that they do not have anything to disclose regarding funding or conflict of interest with respect to this manuscript.

PII: S0168-8278(09)00451-6

doi: 10.1016/j.jhep.2009.06.013

Journal of Hepatology
Volume 51, Issue 3 , Pages 426-429 , September 2009

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