Journal of Hepatology
Volume 51, Issue 6 , Pages 1030-1036, December 2009

Transarterial chemotherapy alone versus transarterial chemoembolization for hepatocellular carcinoma: A randomized phase III trial☆

  • Takuji Okusaka

      Affiliations

    • Hepatobiliary and Pancreatic Oncology Division, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 3 3542 2511; fax: +81 3 3542 3815.
    • ,
  • Hiroshi Kasugai

      Affiliations

    • Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    • ,
  • Yasukazu Shioyama

      Affiliations

    • Department of Radiology, Central Hospital and Cancer Center of Ibaraki, Ibaraki, Japan
    • ,
  • Katsuaki Tanaka

      Affiliations

    • Gastroenterological Center, Yokohama City University Medical Center, Kanagawa, Japan
    • ,
  • Masatoshi Kudo

      Affiliations

    • Department of Gastroenterology and Hepatology, Kinki University, Osaka, Japan
    • ,
  • Hiromitsu Saisho

      Affiliations

    • Department of Medicine and Clinical Oncology, Chiba University, Chiba, Japan
    • ,
  • Yukio Osaki

      Affiliations

    • Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Osaka, Japan
    • ,
  • Michio Sata

      Affiliations

    • Division of Gastroenterology, Kurume University, Fukuoka, Japan
    • ,
  • Shigetoshi Fujiyama

      Affiliations

    • Third Department of Internal Medicine, Kumamoto University, Kumamoto, Japan
    • ,
  • Takashi Kumada

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, Gifu, Japan
    • ,
  • Keiko Sato

      Affiliations

    • Genetic Counseling and Clinical Research Unit, Kyoto University School of Public Health, Kyoto, Japan
    • ,
  • Seiichiro Yamamoto

      Affiliations

    • Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan
    • ,
  • Shiro Hinotsu

      Affiliations

    • Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • ,
  • Tosiya Sato

      Affiliations

    • Department of Biostatistics, Kyoto University School of Public Health, Kyoto, Japan

Received 21 February 2009; received in revised form 29 June 2009; accepted 27 July 2009. published online 01 October 2009.

Associate Editor: J.M. Llovet

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☆ The authors who have taken part in this trial do not have a relationship with the manufacturers of the drugs involved either in the past or present and did not receive funding from the manufacturers to carry out their research. This study was supported by a Grant-in-Aid for Cancer Research (Grant No. 11-15) from the Ministry of Health, Labour and Welfare of Japan. Trial registration: UMIN C000000111.

PII: S0168-8278(09)00588-1

doi:10.1016/j.jhep.2009.09.004

Refers to article:

  • Transarterial therapies in HCC: Does embolization increase survival? , 30 September 2009

    Alejandro Forner, Jean-Claude Trinchet
    Journal of Hepatology December 2009 (Vol. 51, Issue 6, Pages 981-983)

Journal of Hepatology
Volume 51, Issue 6 , Pages 1030-1036, December 2009

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