Journal of Hepatology
Volume 52, Issue 2 , Pages 167-175 , February 2010

Distinct antiviral signaling pathways in primary human hepatocytes and their differential disruption by HCV NS3 protease

  • Loubna Jouan

      Affiliations

    • Laboratoire d’immunologie virale, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, 264 René Levesque-Est, PEA 312, Montréal, Québec, Canada H2X 1P1
    • Département de Sciences Biomédicales, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • ,
  • Pierre Melançon

      Affiliations

    • Laboratoire d’immunologie virale, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, 264 René Levesque-Est, PEA 312, Montréal, Québec, Canada H2X 1P1
    • ,
  • Ian-Gaël Rodrigue-Gervais

      Affiliations

    • Laboratoire d’immunologie virale, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, 264 René Levesque-Est, PEA 312, Montréal, Québec, Canada H2X 1P1
    • Département de Microbiologie et Immunologie, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • ,
  • Valérie-Ann Raymond

      Affiliations

    • Laboratoire d’hépatologie cellulaire, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, Montréal, Québec, Canada H2X 1P1
    • ,
  • Subajini Selliah

      Affiliations

    • Laboratoire d’hépatologie cellulaire, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, Montréal, Québec, Canada H2X 1P1
    • ,
  • Geneviève Boucher

      Affiliations

    • Institut de Recherche en Immunologie et en Cancérologie, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • ,
  • Marc Bilodeau

      Affiliations

    • Laboratoire d’hépatologie cellulaire, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, Montréal, Québec, Canada H2X 1P1
    • Département de Médecine, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • ,
  • Nathalie Grandvaux

      Affiliations

    • Laboratoire de signalisation et infections virales, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, Montréal, Québec, Canada H2X 1P1
    • Département de Biochimie, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • ,
  • Daniel Lamarre

      Affiliations

    • Laboratoire d’immunologie virale, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, 264 René Levesque-Est, PEA 312, Montréal, Québec, Canada H2X 1P1
    • Département de Médecine, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • Institut de Recherche en Immunologie et en Cancérologie, Faculté de Médecine, Université de Montréal, Québec, Canada H3C 3J7
    • Corresponding Author InformationCorresponding author. Address: Laboratoire d’immunologie virale, Centre de Recherche du CHUM (CRCHUM), Hôpital Saint-Luc, 264 René Levesque-Est, PEA 312, Montréal, Québec, Canada H2X 1P1. Tel.: +1 514 343 7127; fax: +1 514 343 2165.

Received 30 June 2009 ,Revised 28 August 2009 ,Accepted 1 September 2009.

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PII: S0168-8278(09)00739-9

doi: 10.1016/j.jhep.2009.11.011

Journal of Hepatology
Volume 52, Issue 2 , Pages 167-175 , February 2010

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