« Previous
Next »
Journal of Hepatology
Volume 52, Issue 5
, Pages 635-643
, May 2010
The hepatitis C virus core protein indirectly induces alpha-smooth muscle actin expression in hepatic stellate cells via interleukin-8
References
- . Liver fibrosis. J Clin Invest. 2005;115:209–218
- . Chemokines in the immunopathogenesis of hepatitis C infection. Hepatology. 2009;49:676–688
- Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology. 1997;25:361–367
- . Disease progression in chronic hepatitis C: modifiable and nonmodifiable factors. Gastroenterology. 2008;134:1699–1714
- . Recognition of genetic factors influencing the progression of hepatitis C: potential for personalized therapy. Mol Diagn Ther. 2008;12:209–218
- Genotype 3 is associated with accelerated fibrosis progression in chronic hepatitis C. J Hepatol. 2009;51:655–666
- . A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol. 1986;103:2787–2796
- An in vitro model of hepatitis C virus genotype 3a-associated triglycerides accumulation. J Hepatol. 2005;42:744–751
- . Titering lentiviral vectors: comparison of DNA, RNA and marker expression methods. Gene Ther. 2002;9:1155–1162
- Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut. 2005;54:142–151
- . The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology. 1987;7:680–687
- Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes. Hepatology. 2008;48:799–807
- . Actin-isoform pattern as a marker of normal or pathological smooth-muscle and fibroblastic tissues. Differentiation. 1987;33:232–238
- . Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration. Am J Physiol Cell Physiol. 2006;291:C957–C965
- . Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology. 2004;126:529–540
- HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1. Exp Mol Med. 2005;37:138–145
- Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells. Gastroenterology. 2005;129:246–258
- . Hepatitis C virus genotype 1b as a major risk factor associated with hepatocellular carcinoma in patients with cirrhosis: a seventeen-year prospective cohort study. Hepatology. 2007;46:1350–1356
- . Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis. Hepatology. 2008;48:16–27
- . Epithelial–mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003;112:1776–1784
- The hepatitis B virus X protein induces paracrine activation of human hepatic stellate cells. Hepatology. 2008;47:1872–1883
- Expression of chemokine receptors by subsets of neurons in the central nervous system. J Immunol. 1997;158:2882–2890
- . Cxc chemokine receptor expression on human endothelial cells. Cytokine. 1999;11:704–712
- . Increased expression of the interleukin-8 gene by alveolar macrophages in idiopathic pulmonary fibrosis. A potential mechanism for the recruitment and activation of neutrophils in lung fibrosis. J Clin Invest. 1991;88:1802–1810
- . Expression of interleukin-8 in human obstructive pancreatitis. JOP. 2004;5:138–144
- . Elevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in benign prostatic hyperplasia. Urology. 2008;72:205–213
- . The CXC chemokine cCAF stimulates precocious deposition of ECM molecules by wound fibroblasts, accelerating development of granulation tissue. BMC Cell Biol. 2002;3:13
- Clinical significance of intrahepatic interleukin-8 in chronic hepatitis C patients. Hepatol Res. 2002;24:413–419
- . Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol. 2001;75:6209–6211
- . Intrahepatic interleukin-8 production during disease progression of chronic hepatitis C. Cancer Lett. 2007;251:36–42
- . Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. J Biol Chem. 2003;278:35755–35766
- Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol. 2001;75:6095–6106
- Hepatitis C virus non-structural protein-2 activates CXCL-8 transcription through NF-kappaB. Arch Virol. 2008;153:293–301
- . Upregulation of fibronectin but not of entactin, collagen IV and smooth muscle actin by anaphylatoxin C5a in rat hepatic stellate cells. Histol Histopathol. 2004;19:1165–1174
- Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology. 2003;124:147–159
- Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology. 2007;46:1509–1518
- . IL-8-induced migratory responses through CXCR1 and CXCR2: association with phosphorylation and cellular redistribution of focal adhesion kinase. Biochemistry. 2003;42:2874–2886
- Role of vinculin in regulating focal adhesion turnover. Eur J Cell Biol. 2006;85:487–500
PII: S0168-8278(10)00081-4
doi: 10.1016/j.jhep.2009.10.035
© 2010 European Association for the Study of the Liver. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Journal of Hepatology
Volume 52, Issue 5
, Pages 635-643
, May 2010
