Journal of Hepatology
Volume 52, Issue 5 , Pages 681-689, May 2010

In vivo silencing of Reptin blocks the progression of human hepatocellular carcinoma in xenografts and is associated with replicative senescence

  • Ludovic Ménard

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • L.M. and D.T. contributed equally to this work.
    • ,
  • Danièle Taras

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • L.M. and D.T. contributed equally to this work.
    • ,
  • Aude Grigoletto

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • ,
  • Valérie Haurie

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • ,
  • Alexandra Nicou

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • ,
  • Nathalie Dugot-Senant

      Affiliations

    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • ,
  • Pierre Costet

      Affiliations

    • Université de Bordeaux, Animalerie spécialisée, F-33076 Bordeaux, France
    • ,
  • Benoît Rousseau

      Affiliations

    • Université de Bordeaux, Animalerie A2, F-33076 Bordeaux, France
    • ,
  • Jean Rosenbaum

      Affiliations

    • INSERM U889; Université de Bordeaux, F-33076 Bordeaux, France
    • Université de Bordeaux, Institut Fédératif de Recherches 66, F-33076 Bordeaux, France
    • CHU de Bordeaux, F–33076 Bordeaux, France
    • Corresponding Author InformationCorresponding author. Tel.: +33 5 557 571 594; fax: +33 556 514 077.

Received 26 August 2009; received in revised form 5 December 2009; accepted 9 December 2009. published online 03 March 2010.

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PII: S0168-8278(10)00092-9

doi:10.1016/j.jhep.2009.12.029

Refers to article:

  • New therapeutic targets in HCC: Reptin ATPase and HCC senescence , 17 February 2010

    Carmen Berasain
    Journal of Hepatology May 2010 (Vol. 52, Issue 5, Pages 633-634)

Journal of Hepatology
Volume 52, Issue 5 , Pages 681-689, May 2010

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