Journal of Hepatology
Volume 52, Issue 5 , Pages 705-711 , May 2010

Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice

  • Alison D. McNeilly

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1382 496589; fax: +44 1382 633923.
    • ,
  • David P. Macfarlane

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Emmett O’Flaherty

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Dawn E. Livingstone

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Tijana Mitić

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Kirsty M. McConnell

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Scott M. McKenzie

      Affiliations

    • MRC Blood Pressure Group, Glasgow Cardiovascular Research Centre, University of Glasgow,126 University Place, Glasgow G12 8TA, UK
    • ,
  • Eleanor Davies

      Affiliations

    • MRC Blood Pressure Group, Glasgow Cardiovascular Research Centre, University of Glasgow,126 University Place, Glasgow G12 8TA, UK
    • ,
  • Rebecca M. Reynolds

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Helle C. Thiesson

      Affiliations

    • Physiology and Pharmacology, University of Southern Denmark, DK-5000 Odense C, Denmark
    • ,
  • Ole Skøtt

      Affiliations

    • Physiology and Pharmacology, University of Southern Denmark, DK-5000 Odense C, Denmark
    • ,
  • Brian R. Walker

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    • ,
  • Ruth Andrew

      Affiliations

    • Endocrinology Unit, Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

Received 2 August 2009 ,Revised 30 September 2009 ,Accepted 15 October 2009.

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☆ Funding: This work was supported by grants from the Wellcome Trust, British Heart Foundation, Society for Endocrinology, Medical Research Council, Danish Heart Foundation, and Danish Society of Hypertension.

PII: S0168-8278(10)00094-2

doi: 10.1016/j.jhep.2009.10.037

Journal of Hepatology
Volume 52, Issue 5 , Pages 705-711 , May 2010

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