Journal of Hepatology
Volume 54, Issue 1 , Pages 34-40 , January 2011

Hepatitis E in Italy: A long-term prospective study

Received 5 February 2010 ,Revised 7 June 2010 ,Accepted 9 June 2010.

References 

  1. Jilani N, Das BC, Husain SA, Baweda UK, Chattopadhya D, Gupta RK, et al. Hepatitis E and fulminant hepatic failure during pregnancy. J Gastroenterol Hepatol. 2007;22:676–682
  2. Purcell RH, Emerson SU. Hepatitis E: an emerging awareness of an old disease. J Hepatol. 2008;48:494–503
  3. Aggarwal R, Naiks S. Epidemiology of hepatitis E: current status. J Gastroenterol Hepatol. 2009;24:1484–1493
  4. Schwartz E, Jenks NP, Van Damme P, Galun E. Hepatitis E virus infection in travellers. Clin Infect Dis. 1999;42:1312–1314
  5. Pina S, Buti M, Cotrina M, Piella J, Girones R. HEV identified in serum from human with acute hepatitis and in sewage of animal origin in Spain. J Hepatol. 2000;33:826–833
  6. Tsang TH, Denison EK, Williams HV, Venczel LV, Ginsberg MM, Vugia DJ. Acute hepatitis E infection acquired in California. Clin Infect Dis. 2000;30:618–619
  7. Widdowson MA, Jaspers WJ, van der Poel WH, Verschoor F, de Roda Husman AM, Winter HL, et al. Cluster of cases of acute hepatitis associated with hepatitis E virus infection acquired in The Netherlands. Clin Infect Dis. 2003;36:29–33
  8. Mansuy JM, Peron JM, Abravanel F, Poirson H, Dubois M, Miedouge M, et al. Hepatitis E in the south west of France in individuals who have never visited an endemic area. J Med Virol. 2004;74:419–424
  9. Ijaz S, Arnold E, Banks M, Bendall RP, Cramp ME, Cunningham R, et al. Non-travel-associated hepatitis E in England and Wales: demographic, clinical, and molecular epidemiological characteristics. J Infect Dis. 2005;192:1166–1172
  10. Dalton HR, Bendal L, Ijaz S, Banks M. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis. 2008;8:698–709
  11. Emerson SU, Purcell RH. Hepatitis E virus. In:  Knipe DM,  Howley PM editor. Fields Virology. Philadelphia: Lippincott Williams & Wilkins; 2007;p. 3047–3058
  12. Lu L, Li L, Hagedorn CH. Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Rev Med Virol. 2006;16:5–36
  13. Arankalle VA, Chobe LP, Joshi MV, Chadha MS, Kundu B, Walimbe AM. Human and swine hepatitis E virus from Western India belong to different genotypes. J Hepatol. 2002;36:417–425
  14. Cooper K, Huang FF, Batista L, Rayo CD, Bezanilla JC, Toth TE, et al. Identification of genotype 3 hepatitis E virus (HEV) in serum and fecal samples pigs in Thailand and Mexico, where genotype 1 and 2 HEV strains are prevalent in the respective human populations. J Clin Microbiol. 2005;43:1684–1688
  15. Mushahwar IK. Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. J Med Virol. 2008;80:646–658
  16. Hsieh S-Y, Meng X-J, Wu Y-H, Liu S-T, Tam AW, Lin D-Y, et al. Identity of a novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates of human hepatitis E virus. J Clin Microbiol. 1999;37:3828–3834
  17. Zanetti AR, Dawson GJ and the Study Group of Hepatitis E. Hepatitis E in Italy: a seroepidemiological survey. J Med Virol. 1994;42:318–320
  18. Coppola RC, Masia G. Seroprevalence and epidemiological features of hepatitis E virus infection in Italy. In:  Rizzetto M,  Purcell RH,  Jerin J,  Verme G editor. Viral hepatitis and liver disease. Torino: Minerva; 1997;p. 609–611
  19. Montella F, Rezza G, Di Sora F, Pezzotti P, Recchia O. Association between hepatitis E virus and HIV infection in homosexual men. Lancet. 1994;344:1433
  20. Pisanti FA, Coppola A, Galli C. Association between hepatitis C and hepatitis E viruses in southern Italy. Lancet. 1994;344:746–747
  21. Romanò L, Tanzi E, Brancatelli S, Raimondo G, Galli C, Zanetti AR. Prevalence of anti-HEV among patients with chronic viral hepatitis and healthy individuals in Southern Italy. In:  Buisson Y,  Coursaget Y,  Kane M editor. Enterically-transmitted hepatitis viruses. Tours, France: La Simarre; 1996;p. 237–239
  22. Matsubayashi K, Kang JH, Sakata H, Takahashi K, Shindo M, Kato M, et al. A case of transfusion-transmitted hepatitis E caused by blood from a donor infected with hepatitis E virus via zoonotic food-borne route. Transfusion. 2008;48:1368–1375
  23. Schlauder GG, Dasi SM, Zanetti AR, Tassopoulos NC, Mushahwar IK. Novel hepatitis E virus (HEV) isolates from Europe: evidence for additional genotypes of HEV. J Med Virol. 1999;57:243–251
  24. Zanetti AR, Schlauder GG, Romanò L, Tanzi E, Fabris P, Dawson GJ, et al. Identification of a novel variant of hepatitis E virus in Italy. J Med Virol. 1999;57:356–360
  25. Kwo PY, Schlauder GG, Carpenter HA, Murphy PJ, Rosemblatt JE, Dawson GJ, et al. Acute hepatitis E by a new isolate acquired in the United States. Mayo Clin Proc. 1997;72:1133–1136
  26. Schlauder GG, Dawson GJ, Erker JC, Kwo PY, Knigge MF, Smalley DL, et al. The sequence and phylogenetic analysis of a novel hepatitis E virus isolated from a patient with acute hepatitis reported in the United States. J Gen Virol. 1998;79:447–456
  27. Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, et al. A novel virus in swine is closely related to the human hepatitis E virus. Proc Natl Acad Sci USA. 1997;94:9860–9865
  28. Gerolami R, Moal V, Colon P. Chronic hepatitis E with cirrhosis in a kidney-transplant recipient. N Engl J Med. 2008;258:859–860
  29. Haagsma EB, van den Berg AP, Porte RJ, Benne CA, Vennema H, Reimerink JH, et al. Chronic hepatitis E virus infection in liver transplant recipients. Liver Transpl. 2008;14:547–553
  30. Kamar N, Selves J, Mansuy JM, Ouezzani L, Peron JM, Guitard J, et al. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med. 2008;358:811–817
  31. Bihl F, Negro F. Chronic hepatitis E in the immunosuppressed: a new source of trouble?. J Hepatol. 2009;50:435–437
  32. Shrestha SM, Shreshta S, Tsuda F, Nishizawa T, Gotanda Y, Takeda N, et al. Molecular investigation of hepatitis E virus infection in patients with acute hepatitis in Kathmandu, Nepal. J Med Virol. 2003;69:207–214
  33. Kumar S, Tamura K, Jakobsen IB, Nei M. Molecular evolutionary genetics analysis software. Bioinformatics. 2001;17:1244–1245Available from: http://www.megasoftware.net/
  34. Garkavenko O, Obriadina A, Meng J, Anderson DA, Bernard HJ, Schroeder BA, et al. Detection and characterisation of swine hepatitis E virus in New Zealand. J Med Virol. 2001;62:525–529
  35. Banks M, Heath GS, Grierson SS, King DP, Gresham A, Girones R, et al. Evidence for the presence of hepatitis E virus in pigs in the United Kingdom. Vet Rec. 2004;154:223–227
  36. Borgen K, Herremans T, Duizer E, Vennema H, Rutjes S, Bosman A, et al. Non-travel related hepatitis E virus genotype 3 infections in The Netherlands; a case series 2004–2006. BMC Infect Dis. 2008;8:61
  37. Rutjes SA, Lodder WJ, Lodder-Vershoor F, van der Berg HHJL, Vennema H, Duizer E, et al. Sources of hepatitis E virus genotype 3 in The Netherlands. Emerg Infect Dis. 2009;15:381–387
  38. Di Bartolo I, Martelli F, Inglese N, Pourshaban M, Caprioli A, Ostanello F, et al. Widespread diffusion of genotype 3 hepatitis E virus among farming swine in northern Italy. Vet Microbiol. 2008;132:47–55
  39. Martelli F, Toma S, Di Bartolo I, Caprioli A, Ruggeri FM, Lelli D, et al. Detection of Hepatitis E Virus (HEV) in Italian pigs displaying different pathological lesions. Res Vet Sci. 2010;88:492–496
  40. Martelli F, Caprioli A, Zengarini M, Marata A, Fiegna C, Di Bartolo I, et al. Detection of hepatitis E virus (HEV) in a demographic managed wild boar (Sus scrofa scrofa) population in Italy. Vet Microbiol. 2008;126:74–81
  41. Martinelli N, Luppi A, Lelli D, Sozzi E, Canelli E, Moreno Martin AM, et al. Prevalence of hepatitis E virus antibodies among pigs in northern Italy. XXXV Meeting Annuale Società Italiana di Patologia ed Allevamento dei Suini, 12–13 marzo 2009, Modena. p. 431–437.
  42. Dalton HR, Stableforth W, Thurairajah P, Hazeldine S, Remnarace R, Usama W, et al. Autochthonous hepatitis E in Southwest England: natural history, complications and seasonal variation, and hepatitis E virus IgG seroprevalence in blood donors, the elderly and patients with chronic liver disease. Eur J Gastroenterol Hepatol. 2008;20:784–790
  43. Wichmann O, Achimanski S, Koch J, Kohler M, Rothe C, Plentz A, et al. Phylogenetic and case-control study on hepatitis E virus infection in Germany. J Infect Dis. 2008;198:1732–1741
  44. Legrand-Abravanel F, Mansuy JM, Dubois M, Kamar N, Peron JM, Rostaing L, et al. Hepatitis E virus genotype 3 diversity, France. Emerg Infect Dis. 2009;15:110–114
  45. Peralta B, Mateu E, Casas M, de Deus N, Martin M, Pina S. Genetic characterization of the complete coding regions of genotype 3 hepatitis E virus isolated from Spanish swine herds. Virus Res. 2009;139:111–116
  46. Mansuy JM, Abravanel F, Miedouge M, Mengelle C, Merviel C, Dubois M, et al. Acute hepatitis E in south-west France over a 5-years period. J Clin Virol. 2009;44:74–77
  47. Norder H, Sundqvist L, Magnusson L, Ostergaard Breum S, Lofdahl M, Breum S, et al. Endemic hepatitis E in two Nordic countries. Euro Surveill. 2009;14(19):
  48. Yazaki Y, Mizuo H, Takahashi M, Nishizawa T, Sasaki N, Gotanda Y, et al. Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be food-borne, as suggested by the presence of hepatitis E virus in pig liver as food. J Gen Virol. 2003;84:2351–2357
  49. Matsuda H, Okada K, Takahashi K, Mishiro S. Severe hepatitis E virus infection after ingestion of uncooked liver from a wild boar. J Infect Dis. 2003;188:944
  50. Tei S, Kitajima N, Takahashi K, Mishiro S. Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet. 2003;362:371–373
  51. Takahashi K, Kitajima N, Abe N, Mishiro S. Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer. Virology. 2004;330:501–505
  52. Tamada Y, Yano K, Yatsuhashi H, Inoue O, Mawatari F, Ishibashi H. Consumption of wild boar linked to cases of hepatitis E. J Hepatol. 2004;40:869–870
  53. Bouwknegt M, Lodder-Verschoor F, van der Poel WH, Rutjes SA, Roda Husman AM. Hepatitis E virus RNA in commercial porcine livers in The Netherlands. J Food Prot. 2007;70:2889–2895
  54. Feagins AR, Opriessnig T, Guenette DK, Halbur PG, Meng XJ. Detection and characterization of infectious hepatitis E virus from commercial pig liver sold in local grocery stores in the USA. J Gen Virol. 2007;88:912–917
  55. Shrestha MP, Scott RM, Joshi DM, Mammen MP, Thapa N, Myint KS, et al. Safety and efficacy of a recombinant hepatitis E vaccine. N Engl J Med. 2007;356:895–903
  56. Zhang J, Liu CB, Li RC, Li YM, Zheng YJ, Li YP, et al. Randomized-controlled phase II clinical trial of a bacterically expressed recombinant hepatitis E vaccine. Vaccine. 2009;27:1869–1874

PII: S0168-8278(10)00707-5

doi: 10.1016/j.jhep.2010.06.017

Journal of Hepatology
Volume 54, Issue 1 , Pages 34-40 , January 2011