Treatment with lamivudine (LAM) rapidly inhibits viral replication in most patients
with chronic liver disease related to hepatitis B virus (HBV), but the development
of drug-resistant viral mutants [
[1]
] limits its long-term effectiveness.To read this article in full you will need to make a payment
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References
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- Reduced antigenicity of the hepatitis B virus HBsAg protein arising as a consequence of sequence changes in the overlapping polymerase gene that are selected by lamivudine therapy.Virology. 2002; 293: 305-313
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© 2003 Published by Elsevier Inc.
