Summary
Percutaneous treatment of hepatocellular carcinoma (HCC) encompasses a vast range
of techniques, including monopolar radiofrequency ablation (RFA), multibipolar RFA,
microwave ablation, cryoablation and irreversible electroporation. RFA is considered
one of the main curative treatments for HCC of less than 5 cm developing on cirrhotic
liver, together with surgical resection and liver transplantation. However, controversies
exist concerning the respective roles of ablation and liver resection for HCC of less
than 3 to 5 cm on cirrhotic liver. In line with the therapeutic algorithm of early
HCC, percutaneous ablation could also be used as a bridge to liver transplantation
or in a sequence of upfront percutaneous treatment, followed by transplantation if
the patient relapses. Moreover, several innovations in ablation methods may help to
efficiently treat early HCC, initially considered as “non-ablatable”, and might, in
some cases, extend ablation criteria beyond early HCC, enabling treatment of more
patients with a curative approach.
Keywords
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Article info
Publication history
Published online: October 13, 2017
Accepted:
October 6,
2017
Received in revised form:
October 1,
2017
Received:
September 6,
2017
Identification
Copyright
© 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
