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Acute liver failure: Do the EASL guidelines address the whole spectrum?

  • Manuel Mendizabal
    Correspondence
    Corresponding author. Address: Hepatology and Liver Transplant Unit, Hospital Universitario Austral, Pilar, Buenos Aires, Argentina. Tel.: +54 91140332244; fax: +54 2304482236.
    Affiliations
    Hepatology and Liver Transplant Unit, Hospital Universitario Austral, Pilar, Buenos Aires, Argentina
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  • Marcelo Silva
    Affiliations
    Hepatology and Liver Transplant Unit, Hospital Universitario Austral, Pilar, Buenos Aires, Argentina
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Published:November 10, 2017DOI:https://doi.org/10.1016/j.jhep.2017.08.041
      We read with great interest the latest European Association for the Study of the Liver (EASL) clinical practice guideline (CPG) on the management of acute liver failure (ALF).
      EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure.
      ALF is a rare and a rapidly progressive form of liver disease that is associated with high mortality. Therefore, CPGs are critical to assist physicians and other healthcare providers in the clinical evaluation and therapeutic decision-making processes. These documents describe the global impact of specific liver diseases with a range of accepted approaches for their diagnosis and treatment.

      Linked Article

      • EASL Clinical Practical Guidelines on the management of acute (fulminant) liver failure
        Journal of HepatologyVol. 66Issue 5
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          The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. In the context of hepatological practice, however, ALF refers to a highly specific and rare syndrome, characterised by an acute abnormality of liver blood tests in an individual without underlying chronic liver disease. The disease process is associated with development of a coagulopathy of liver aetiology, and clinically apparent altered level of consciousness due to hepatic encephalopathy.
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