Reply to: “Energy drinks and adolescents – A hepatic health hazard?”

Valerio Nobili; A. Mosca; E. Scorletti; Christopher D. Byrne

doi:10.1016/j.jhep.2017.11.021

Letter to the Editor| Volume 68, ISSUE 4, P857-858, April 2018

Reply to: “Energy drinks and adolescents – A hepatic health hazard?”

Valerio Nobili
Valerio Nobili
Correspondence
Corresponding author. Address: Department of Pediatric – University “La Sapienza”, and Hepatometabolic Disease Unit, Bambino Gesù Children’s Hospital IRCCS (Instituto di Ricovero e Cura a Carattere Scientifico), P.le S. Onofrio, 4 – 00165 Rome, Italy. Tel.: +39 06 68592192.
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Hepatometabolic Unit – Bambino Gesù Children’s Hospital – Rome, Italy
Department of Pediatric – University “La Sapienza” – Rome, Italy
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A. Mosca
A. Mosca
Affiliations
Hepatometabolic Unit – Bambino Gesù Children’s Hospital – Rome, Italy
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E. Scorletti
E. Scorletti
Affiliations
Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom
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Christopher D. Byrne
Christopher D. Byrne
Affiliations
Human Development and Health Academic Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, United Kingdom
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Published:November 23, 2017DOI:https://doi.org/10.1016/j.jhep.2017.11.021

We read with interest the letter by Robin et al. referring to our paper entitled “Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents”.

¹

Robin S, Buchanan R, Poole R. Energy drinks and adolescents – A hepatic health hazard? J Hepatol 2018;68:856–857.

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^,

²

Mosca A.
Nobili V.
De Vito R.
Crudele A.
Scorletti E.
Villani A.
et al.

Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents.

In their letter, the authors report the case of a 17-year-old-boy who developed NASH due to his unhealthy lifestyle and his consumption of energy drinks (EDs). Robin et al. also highlight that other components of the diet, such as niacin, xanthine, taurine and B vitamins, could contribute to liver damage.

^[1]

Robin S, Buchanan R, Poole R. Energy drinks and adolescents – A hepatic health hazard? J Hepatol 2018;68:856–857.

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Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents
Journal of HepatologyVol. 66Issue 5
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  Non-alcoholic fatty liver disease (NAFLD) is now largely regarded as the hepatic manifestation of metabolic syndrome (MetS) and NAFLD represents the most frequent chronic liver disease in children in Western countries [1]. NAFLD begins with the development of liver lipid accumulation and the condition progresses over time with the development of liver inflammation and fibrosis (non-alcoholic steatohepatitis or NASH). Although it was initially thought that NAFLD was a relatively harmless condition in children and adolescents, recent evidence shows that NASH occurs in this young population [2].
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Energy drinks and adolescents – A hepatic health hazard?
Journal of HepatologyVol. 68Issue 4
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  We read with great interest the paper entitled “Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents”, published by Mosca et al. in the Journal of Hepatology, 2017.¹
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References

Robin S, Buchanan R, Poole R. Energy drinks and adolescents – A hepatic health hazard? J Hepatol 2018;68:856–857.
View in Article
- Google Scholar
- Mosca A.
- Nobili V.
- De Vito R.
- Crudele A.
- Scorletti E.
- Villani A.
- et al.
Serum uric acid concentrations and fructose consumption are independently associated with NASH in children and adolescents.
J Hepatol. 2017; 66: 1031-1036
View in Article
- Huang B.
- Kunkel D.
- Kabany M.E.
Acute liver failure following one year of daily consumption of a sugar-free energy drink.
ACG Case Rep J. 2014; 1: 214-216
View in Article
- PubMed
- Google Scholar
WHO: www.apps.who.int/iris/bitstream/10665/149782/1/9789241549028_eng.pdf. Guideline: sugars intake for adults and children: draft guidelines on free sugars released for public consultation, WHO, 2014.
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Published online: November 23, 2017

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