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Letter to the Editor| Volume 68, ISSUE 4, P863-864, April 2018

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Reply to: “Detecting microvascular invasion in HCC with contrast-enhanced MRI: Is it a good idea?”

  • Sunyoung Lee
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-gu, Seoul 06351, Republic of Korea
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  • Seong Hyun Kim
    Correspondence
    Corresponding author. Address: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-gu, Seoul 06351, Republic of Korea. Tel.: +82 2 3410 0511; fax: +82 2 3410 0084.
    Affiliations
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-Ro, Gangnam-gu, Seoul 06351, Republic of Korea
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Published:December 27, 2017DOI:https://doi.org/10.1016/j.jhep.2017.12.020
Reply to: “Detecting microvascular invasion in HCC with contrast-enhanced MRI: Is it a good idea?”
Previous ArticleDetecting microvascular invasion in HCC with contrast-enhanced MRI: Is it a good idea?
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      We thank Teh-Ia Huo et al. for their interest in our recent study about preoperative gadoxetic acid–enhanced MRI for predicting microvascular invasion (MVI) in patients with single hepatocellular carcinoma (HCC),
      • Lee S.
      • Kim S.H.
      • Lee J.E.
      • Sinn D.H.
      • Park C.K.
      Preoperative gadoxetic acid-enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma.
      J Hepatol. 2017; 67: 526-534
      and we appreciate their comments.

      Linked Article

      • Preoperative gadoxetic acid–enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma
        Journal of HepatologyVol. 67Issue 3
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          Vascular invasion, either macrovascular or microvascular invasion (MVI), is a well-known major prognostic factor of hepatocellular carcinoma (HCC), after surgical resection or liver transplantation.1–4 In particular, MVI of HCC is a major risk factor for early recurrence during the first 2 years after curative treatment.5,6 Although macrovascular invasion can be frequently detected prior to surgery by complementary imaging modalities, including computed tomography (CT) and magnetic resonance (MR) imaging, MVI can rarely be determined preoperatively because it is a histopathological diagnosis.
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      • Detecting microvascular invasion in HCC with contrast-enhanced MRI: Is it a good idea?
        Journal of HepatologyVol. 68Issue 4
        • Preview
          We have read with interest the paper “Preoperative gadoxetic acid-enhanced MRI for predicting microvascular invasion in patients with single hepatocellular carcinoma” by Drs. S. Lee et al. published in a recent issue of the Journal of Hepatology.1 This study clearly described the feasibility of contrast-enhanced MRI by using gadoxetic acid to detect microvascular invasion (mVI) in a surgical cohort of patients with hepatocellular carcinoma (HCC) ≤5 cm in diameter. Although their findings highlight the role of contrast-enhanced MRI for small HCC, a few concerns may need attention to justify its usefulness in clinical practice.
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      Article info

      Publication history

      Published online: December 27, 2017

      Identification

      DOI: https://doi.org/10.1016/j.jhep.2017.12.020

      Copyright

      © 2018 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

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