Abstract
Background/Aims: The aim of this study was to determine the outcome of asymptomatic liver hydatid
cysts in a cohort of 33 out of 59 carriers by evaluating clinical and ultrasonographic
(US) changes 10–12 years after initial diagnosis.
Methods: We compared US features and cyst size with the original descriptions from 1984–1986.
Patients were questioned about hydatid-related symptoms and signs.
Results: Thirty-three of the 59 carriers could be reevaluated, five (15.2%) of whom had undergone
surgery without presenting symptoms, while of 28 unoperated cases, 21 (75%) remained
asymptomatic. Of the unoperated cases evaluated by US, in 8/14 (57.1%) there were
no modifications in cyst size during the 10-12-year period, in five (35.7%) growth
was slight (<3 cm) and in one (7.1%) the cyst grew 4 cm. Mean cyst growth in all 14
cases was 0.7 cm.
Conclusions: Despite the limited number of cases, our results show that most asymptomatic liver
hydatid cases (75%) remain symptom-free for more than 10 years, regardless of cyst
size or type. We believe that such carriers are at low risk of developing complications,
so that it is difficult to establish specific rules for their therapy, if any. Longitudinal
follow-up of larger series of asymptomatic hepatic hydatidosis cases is essential
to gain a deeper insight into the natural history of such patients, and to draw up
comprehensive guidelines for treatment.
Keywords
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References
- Hydatidosis: a global problem of increasing importance.Bull World Health Organ. 1977; 55: 499-507
- Control de la hidatidosis en la Provincia de Rio Negro. Evaluación actividades atención médica.Rev Sanid Hig Pública. 1993; 5: 377-384
- Catastro ecográfico, serológico y radiológico de hidatidosis humana.Acta Latinoam Gastroenterol. 1985; 4: 199-211
- Portable ultrasound scanner versus serology in screening for hydatid cysts in a nomadic population.Lancet. 1987; ii: 259-261
- Frecuencia de las localizaciones hepática y pulmonar del quiste hidatídico en pacientes sintomáticos y en portadores asintomáticos de áreas endémicas.Rev Ibérica Parasitol. 1988; 48: 149-153
- Hidatidosis hepática. Aporte de la Ultrasonografia y de la Autopsia al conocimiento de su Historia Natural. (Res) Congreso Extraordinario del V Centenario del Encuentro entre España y América.Hepatología y Gastroenterología (Spain). May, 1992;
- Asymptomatic abdominal hydatidosis detected by ultrasonography.Acta Radiol. 1988; 29: 431-434
- Liver hydatidosis.Acta Latinoam Gastroenterol. 1996; 26: 199-200
- Standardization and evaluation of an enzyme immunoassay as a screening test for the seroepidemiology of human hydatidosis.Am J Trop Med Hyg. 1986; 35: 1000-1005
- Seroepidemiology of human hydatidosis: use of dried blood samples on filter paper.Trans R Soc Trop Med Hyg. 1988; 38: 603-607
- Detection of antibodies against Echinococcus granulosus arc 5 antigens by double diffusion test.Trans R Soc Trop Med Hyg. 1978; 72: 226-229
- El problema de las localizaciones del quiste hidatídico en el hombre.Bol Chil Parasitol. 1971; 26: 106-114
- Frequency of hydatidosis in autopsies performed at the Institute of Legal Medicine and 8 Hospitals of Santiago, Chile, 1947–1970.Bol Chil Parasitol. 1971; 98: 98-103
- Hidatidosis en el Uruguay Estudio epidemiológico 1962–68.El Tórax. 1970; 19: 1-15
- Hidatidosis en el Uruguay.Bol Sanit Panam. 1975; 6: 519-529
- Advances in clinical management of cystic echinococcosis.Editorial. Acta Trop. 1997; 64: 1-4
- Detection, screening and community epidemiology of taenid cestode zoonoses: cystic echinococcosis, alveolar echinococcosis and neurocysticercosis.Adv Parasitol. 1996; 38: 169-250
- Abdominal cystic hydatid diseases (CHD): classification of sonographic appearance and response to treatment.J Clin Ultrasound. 1996; 24: 491-500
- John Libbey CIC: XV Extraordinary Congress for the Celebration of 50 Years of A.I.H., Rome. Nov. 4–8 1991; : 277-286
- Kyste hydatique du foie.Gastroenterol Clin Biol. 1995; 19: B110-B118
- WHO Informal Working on Echinococcosis Guidelines for treatment of cystic and alveolar echinococcosis in humans.Bull World Health Organ. 1996; 74: 231-242
- Randomised controlled trial of efficacy of albendazol in intra-abdominal hydatid disease.Lancet. 1993; 342: 1269-1272
- Chemotherapy of human cystic echinococcosis: comparative efficacy of mebendazole and albendazole.Ann Trop Med Parasitol. 1992; 86: 59-66
- Advances of medical treatment of human hydatidosis.Recent Prog Med. 1996; 87: 346-352
- A new therapeutic approach for hydatid liver cysts: aspiration and alcohol injection under sonographic guidance.Gastroenterology. 1990; 98: 1366-1368
- Progress in surgical treatment of hydatid disease in China. A clinical analysis of 22,005 surgical cases.Chin Med J. 1995; 108: 295-299
- Percutaneous drainage versus albendazole therapy in hepatic hydatidosis: a prospective, randomized study.Gastroenterology. 1993; 104: 1452-1459
- Percutaneous drainage compared with surgery for hepatic hydatid cysts.N Engl J Med. 1997; 337: 881-887
- Principles of the surgical approach in human liver cystic echinococcosis.Acta Trop. 1997; 64: 109-122
- Resolution of hydatid liver cyst by spontaneous rupture into the biliary tract.J Hepatol. 1997; 26: 1408-1412
- Use of PAIR in human cystic echinococcosis.Acta Trop. 1997; 64: 95-107
- Liver hydatid disease: long-term results of percutaneous treatment.Radiology. 1996; 198: 259-264
- Three to 7-year follow-up after albendazole treatment of 68 patients with cystic echinococcosis (hydatid disease).Ann Trop Med Parasitol. 1994; 88: 295-304
Article info
Publication history
Accepted:
August 13,
1998
Received in revised form:
August 7,
1998
Received:
April 27,
1998
Identification
Copyright
© 1999 Published by Elsevier Inc.