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Correspondence| Volume 30, ISSUE 2, P349-350, February 1999

Elevated liver enzymes preceding vessel involvement in Takayasu's arteritis

      Takayasu's arteritis is an inflammatory and stenotic disease primarily affecting medium- and large-sized arteries. It is prevalent mostly in young females in Asia, but is being increasingly detected in Western Europe, North America, and Africa (
      • Kerr GS
      • Hallahan CW
      • Giordano J
      • et al.
      Takayasu arteritis.
      ). The disorder is strongly suspected in patients with decreased or absent peripheral pulses, blood pressure discrepancies, and arterial bruits. Diagnosis is confirmed by arteriography and histopathology. Laboratory tests recommended in the latest reviews and textbooks (
      • Kerr GS
      • Hallahan CW
      • Giordano J
      • et al.
      Takayasu arteritis.
      ,
      • Kerr GS
      Takayasu's arteritis.
      ,
      • Hall S
      • Buchbinder R
      Takayasu's arteritis.
      ,
      • Fauci AS
      The vasculitis syndrome.
      ) are limited to an unspecifically elevated erythrocyte sedimentation rate (ESR) and a slightly lowered haemoglobin. Abnormal liver enzymes are not included. We report a case of elevated liver enzymes preceding the characteristic large vessel changes.
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        • Giordano J
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        Takayasu arteritis.
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