September 2010

Editorial Board
Published in issue: September 2010
i

EASL Fellowship program
Published in issue: September 2010
ii

Berlin International Liver Conference
Published in issue: September 2010
iii

Monothematic Conference: Athens
Published in issue: September 2010
iv

Monothematic Conference: Call for Proposals
Published in issue: September 2010
v

Contents
Published in issue: September 2010
vii-viii

Focus

Focus
• Daniel Shouval
Published online: June 11, 2010
p395-396
Open Access

EASL Clinical Practice Guideline

EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis
• European Association for the Study of the Liver
Published online: June 07, 2010
p397-417

Editorials

Pharmacokinetic and pharmacodynamic modeling of pegylated-interferon alfa
• Rositsa B. Dimova,
• Andrew H. Talal
Published online: June 03, 2010
p418-420
Open Access

Host and viral determinants for engraftment of virus permissive human hepatocytes into chimeric immunodeficient mice
• Eric Robinet,
• Thomas F. Baumert
Published online: June 04, 2010
p421-423
Open Access

Research Articles

Viral Hepatitis


Altered interferon-α-signaling in natural killer cells from patients with chronic hepatitis C virus infection
• Takuya Miyagi,
• Tetsuo Takehara,
• Kumiko Nishio,
• ...
• Naoki Hiramatsu,
• Tatsuya Kanto,
• Norio Hayashi
Published online: May 31, 2010
p424-430

Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: Possible role for molecular mimicry
• Salvatore Sutti,
• Matteo Vidali,
• Cristina Mombello,
• Massimo Sartori,
• Magnus Ingelman-Sundberg,
• Emanuele Albano
Published online: June 08, 2010
p431-438

Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients
• Hiromi Abe,
• Hidenori Ochi,
• Toshiro Maekawa,
• ...
• Michiaki Kubo,
• Yusuke Nakamura,
• Kazuaki Chayama
Published online: June 04, 2010
p439-443

Natural history of chronic hepatitis C: Genotype 1 versus genotype 6
• Wai-Kay Seto,
• Ching-Lung Lai,
• James Fung,
• ...
• John Young,
• Danny Ka-Ho Wong,
• Man-Fung Yuen
Published online: June 02, 2010
p444-448

Lamivudine plus adefovir or entecavir for patients with chronic hepatitis B resistant to lamivudine and adefovir
• Nae-Yun Heo,
• Young-Suk Lim,
• Han Chu Lee,
• Young-Hwa Chung,
• Yung Sang Lee,
• Dong Jin Suh
Published online: June 14, 2010
p449-454

Thrombocytopenia and the risk of bleeding during treatment with peginterferon alfa and ribavirin for chronic hepatitis C
• Robert Roomer,
• Bettina E. Hansen,
• Harry L.A. Janssen,
• Robert J. de Knegt
Published online: June 04, 2010
p455-459

Pharmacodynamics of PEG-IFN-α-2a in HIV/HCV co-infected patients: Implications for treatment outcomes
• Harel Dahari,
• Evaldo S. Affonso de Araujo,
• Bart L. Haagmans,
• ...
• Scott J. Cotler,
• Antonio A. Barone,
• Avidan U. Neumann
Published online: June 03, 2010
p460-467

Factors determining successful engraftment of hepatocytes and susceptibility to hepatitis B and C virus infection in uPA-SCID mice
• Thomas Vanwolleghem,
• Louis Libbrecht,
• Bettina E. Hansen,
• ...
• Tania Roskams,
• Philip Meuleman,
• Geert Leroux-Roels
Published online: June 08, 2010
p468-476

Cirrhosis


A new highly sensitive point of care screen for spontaneous bacterial peritonitis using the leukocyte esterase method
• Michel Henry Mendler,
• Arun Agarwal,
• Mateen Trimzi,
• ...
• Gabriel David,
• Adrienne Workman,
• Bruce Runyon
Published online: June 04, 2010
p477-483

Mannose-binding lectin deficiency confers risk for bacterial infections in a large Hungarian cohort of patients with liver cirrhosis
• Istvan Altorjay,
• Zsuzsanna Vitalis,
• Istvan Tornai,
• ...
• Antal Csepregi,
• Peter Laszlo Lakatos,
• Maria Papp
Published online: June 11, 2010
p484-491

Liver Failure and Growth


Meta-analysis of performance of Kings’s College Hospital Criteria in prediction of outcome in non-paracetamol-induced acute liver failure
• Mark J.W. McPhail,
• Julia A. Wendon,
• William Bernal
Published online: June 11, 2010
p492-499

Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury
• Cornelia S. Viebahn,
• Volker Benseler,
• Lauren E. Holz,
• ...
• Patrick Bertolino,
• Ruth Ganss,
• George C.T. Yeoh
Published online: June 14, 2010
p500-507

Cancer


Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: Evidence from an updated meta-analysis
• Bin Wang,
• Gang Huang,
• Dan Wang,
• ...
• Ran Dong,
• Deqiang Zhang,
• Weiping Zhou
Published online: June 04, 2010
p508-518

Molecular and Cell Biology


The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes
• Ahmed M. Elsharkawy,
• Fiona Oakley,
• Feng Lin,
• Graham Packham,
• Derek A. Mann,
• Jelena Mann
Published online: June 10, 2010
p519-527
Open Access

Preservation of basal AcSDKP attenuates carbon tetrachloride-induced fibrosis in the rat liver
• Yuan-Wen Chen,
• Bo-Wei Liu,
• Yu-Jian Zhang,
• ...
• Betty Pat,
• Jiang-Gao Fan,
• Ding-Guo Li
Published online: June 08, 2010
p528-536

Cholestasis and Autoimmune Diseases

Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients
• Satoru Joshita,
• Takeji Umemura,
• Kaname Yoshizawa,
• ...
• Hiromi Ishibashi,
• Masao Ota
• The Shinshu PBC Study Group
Published online: June 14, 2010
p537-541

Genetic and Metabolic Diseases


Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis
• Quentin M. Anstee,
• Danilo Concas,
• Hiromi Kudo,
• ...
• Howard C. Thomas,
• Mark R. Thursz,
• Robert D. Goldin
Published online: June 14, 2010
p542-550

Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease
• Valentina Medici,
• Janet M. Peerson,
• Sally P. Stabler,
• ...
• John R. Richards,
• Lorenzo Rossaro,
• Charles H. Halsted
Published online: June 04, 2010
p551-557

Reviews

Hepatic endothelial dysfunction and abnormal angiogenesis: New targets in the treatment of portal hypertension
• Jaume Bosch,
• Juan G. Abraldes,
• Mercedes Fernández,
• Juan Carlos García-Pagán
Published online: June 04, 2010
p558-567
Open Access

Epigenetic regulation of cancer stem cells in liver cancer: Current concepts and clinical implications
• J.U. Marquardt,
• V.M. Factor,
• S.S. Thorgeirsson
Published online: June 04, 2010
p568-577
Open Access

Special Sections

International Hepatology

Genomic tracing of the elusive liver cancer ancestor
• Helena Cornellà,
• Augusto Villanueva
Published online: June 04, 2010
p578-579
Open Access

Rifaximin in hepatic encephalopathy: More than just a non-absorbable antibiotic?
• Rajiv Jalan
Published online: June 04, 2010
p580-582
Open Access

Hepatology Snapshot


Hepatitis C virus replication cycle
• Ralf Bartenschlager,
• Francois-Loic Cosset,
• Volker Lohmann
Published online: June 04, 2010
p583-585
Open Access

Letters to the Editor

Pro-coagulant imbalance in patients with chronic liver disease
• Armando Tripodi,
• Massimo Primignani,
• Veena Chantarangkul,
• Pier Mannuccio Mannucci
Published online: June 04, 2010
p586-587
Open Access
Non-alcoholic fatty liver disease, alcohol intake and psoriasis
• Matteo Bordignon,
• Guido Viel,
• Andrea Peserico,
• Mauro Alaibac
Published online: June 04, 2010
p587
Open Access
Which transarterial therapy is best for hepatocellular carcinoma? – The evidence to date
• Emmanuel Tsochatzis,
• Tim Meyer,
• Laura Marelli,
• Andrew K. Burroughs
Published online: March 24, 2010
p588
Open Access
Evaluation of renal function in patients with cirrhosis
• Evangelos Cholongitas,
• Elias Xirouchakis,
• Matteo Garcovich,
• A.K. Burroughs
Published online: March 24, 2010
p589
Open Access

Retraction

Retraction notice to ”Intraperitoneal application of caffeine prevents D-galactosamine induced hepatic expression of connective tissue growth factor (CTGF/CCN2) in the rat” [JHEPAT 50 (2009) 1053–1055]
• Olav A. Gressner,
• Monika Siluschek,
• Birgit Lahme,
• Axel M. Gressner
Published online: June 09, 2010
p590