Table of Contents page: Journal of Hepatology

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Editorial Board

Published in issue: July 2015

iii

EASL Monothematic Conference, Autoimmune Hepatitis. London, United Kingdom, 2015

Published in issue: July 2015

iv

EASL Special Conference, Addressing End-Stage Liver Disease, a Multifaceted Challenge. Glasgow, United Kingdom, 2015

Published in issue: July 2015

v

EASL 2015 Short-Term Research Fellowship Programme

Published in issue: July 2015

vi

EASL Basic School of Hepatology Course 11: T-cell Responses in Viral Hepatitis and Hepatocellular Carcinoma. Freiburg-Breisgau, Germany, 2016

Published in issue: July 2015

vii

The International Liver Congress. Barcelona, Spain, 2016

Published in issue: July 2015

xii

From the Editor’s desk...

Richard Moreau,
Ramon Bataller,
Thomas Berg,
Jessica Zucman-Rossi,
Rajiv Jalan

Published online: April 20, 2015

p1-4

Open Access

Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity

Neil Kaplowitz,
Sanda Win,
Tin Aung Than,
Zhang-Xu Liu,
Lily Dara

Published online: March 11, 2015

p5-7

Open Access

Metabolic syndrome-associated hepatocellular carcinoma: Questions still unanswered

Timothy M. Pawlik,
Olivier Soubrane

Published online: April 07, 2015

p8-9

Open Access

Exercise and improvement of NAFLD: Practical recommendations

Rohit Loomba,
Helena Cortez-Pinto

Published online: April 07, 2015

p10-12

Open Access

Research Articles

Viral Hepatitis

Decades after recovery from hepatitis B and HBsAg clearance the CD8⁺ T cell response against HBV core is nearly undetectable

Helenie Kefalakes,
Christoph Jochum,
Gudrun Hilgard,
...
Guido Gerken,
Michael Roggendorf,
Joerg Timm

Published online: January 31, 2015

p13-19

Drug-drug interaction profile of the all-oral anti-hepatitis C virus regimen of paritaprevir/ritonavir, ombitasvir, and dasabuvir

Rajeev M. Menon,
Prajakta S. Badri,
Tianli Wang,
...
Thomas J. Podsadecki,
Walid M. Awni,
Sandeep Dutta

Published online: January 31, 2015

p20-29

Open Access

Daclatasvir and asunaprevir plus peginterferon alfa and ribavirin in HCV genotype 1 or 4 non-responders

Donald Jensen,
Kenneth E. Sherman,
Christophe Hézode,
...
Eric Hughes,
Stephanie Noviello
on behalf of the HALLMARK-QUAD Study Team

Published online: February 20, 2015

p30-37

CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation

Tony Bruns,
Henning W. Zimmermann,
Annette Pachnio,
...
Christopher J. Weston,
Paul A. Moss,
David H. Adams

Published online: March 11, 2015

p38-49

Cirrhosis

Submassive hepatic necrosis distinguishes HBV-associated acute on chronic liver failure from cirrhotic patients with acute decompensation

Hai Li,
Qiang Xia,
Bo Zeng,
...
De-Kai Qiu,
Tai-Ling Wang,
Hong-Lei Weng

Published online: January 31, 2015

p50-59

Decreased Tim-3 expression is associated with functional abnormalities of monocytes in decompensated cirrhosis without overt bacterial infection

Yu Shi,
Wei Wu,
Ying Yang,
...
Yihua Wu,
Li Wei,
Zhi Chen

Published online: February 19, 2015

p60-67

Transplantation

Improvement of liver injury and survival by JNK2 and iNOS deficiency in liver transplants from cardiac death mice

Qinlong Liu,
Hasibur Rehman,
Yasodha Krishnasamy,
Rick G. Schnellmann,
John J. Lemasters,
Zhi Zhong

Published online: February 20, 2015

p68-74

Liver Failure and Growth

Metformin ameliorates acetaminophen hepatotoxicity via Gadd45β-dependent regulation of JNK signaling in mice

Yong-Hoon Kim,
Jung Hwan Hwang,
Kyoung-Shim Kim,
...
Yong-Hyeon Yim,
Hueng-Sik Choi,
Chul-Ho Lee

Published online: February 11, 2015

p75-82

Cancer

Does pathological response after transarterial chemoembolization for hepatocellular carcinoma in cirrhotic patients with cirrhosis predict outcome after liver resection or transplantation?

Marc-Antoine Allard,
Mylène Sebagh,
Aldrick Ruiz,
...
Henri Bismuth,
Denis Castaing,
René Adam

Published online: January 31, 2015

p83-92

Liver resection for hepatocellular carcinoma in patients with metabolic syndrome: A multicenter matched analysis with HCV-related HCC

Luca Viganò,
Simone Conci,
Matteo Cescon,
...
Antonio Daniele Pinna,
Alfredo Guglielmi,
Lorenzo Capussotti

Published online: January 31, 2015

p93-101

Targeting cyclin dependent kinase 5 in hepatocellular carcinoma – A novel therapeutic approach

Sandra M. Ehrlich,
Johanna Liebl,
Maximilian A. Ardelt,
...
Stefan Zahler,
Alexander L. Gerbes,
Angelika M. Vollmar

Published online: February 04, 2015

p102-113

Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9

Yao Liu,
Wei Yan,
Samer Tohme,
...
Michael Lotze,
Daolin Tang,
Allan Tsung

Published online: February 11, 2015

p114-121

Prognostic nomogram for patients with unresectable hepatocellular carcinoma after transcatheter arterial chemoembolization

Li Xu,
Zhen-Wei Peng,
Min-Shan Chen,
...
Rong-Ping Guo,
Xiao-Jun Lin,
Wan-Yee Lau

Published online: February 25, 2015

p122-130

Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma

Naoto Fujiwara,
Hayato Nakagawa,
Yotaro Kudo,
...
Kuni Ohtomo,
Shuichiro Shiina,
Kazuhiko Koike

Published online: February 24, 2015

p131-140

Open Access

Molecular and Cell Biology

β-PDGF receptor expressed by hepatic stellate cells regulates fibrosis in murine liver injury, but not carcinogenesis

Peri Kocabayoglu,
Abigale Lade,
Youngmin A. Lee,
...
Philippe Soriano,
Yujin Hoshida,
Scott L. Friedman

Published online: February 09, 2015

p141-147

Protective effect of Th22 cells and intrahepatic IL-22 in drug induced hepatocellular injury

Rongtao Lai,
Xiaogang Xiang,
Ruidong Mo,
...
Hui Wang,
Shisan Bao,
Qing Xie

Published online: February 11, 2015

p148-155

Genetic and Metabolic Diseases

Hepatic steatosis in Wilson disease – Role of copper and PNPLA3 mutations

Albert Friedrich Stättermayer,
Stefan Traussnigg,
Hans-Peter Dienes,
...
Andreas Maieron,
Michael Trauner,
Peter Ferenci

Published online: February 09, 2015

p156-163

PPARα gene expression correlates with severity and histological treatment response in patients with non-alcoholic steatohepatitis

Sven Francque,
An Verrijken,
Sandrine Caron,
...
Peter Michielsen,
Luc Van Gaal,
Bart Staels

Published online: February 20, 2015

p164-173

Effect of aerobic exercise training dose on liver fat and visceral adiposity

Shelley E. Keating,
Daniel A. Hackett,
Helen M. Parker,
...
Ian D. Caterson,
Jacob George,
Nathan A. Johnson

Published online: April 07, 2015

p174-182

Hepatic estrogen receptor α improves hepatosteatosis through upregulation of small heterodimer partner

Xiaolin Wang,
Yan Lu,
E. Wang,
...
Xuefeng Xia,
Shuyu Yang,
Xiaoying Li

Published online: February 23, 2015

p183-190

Restoration of Wnt/β-catenin signaling attenuates alcoholic liver disease progression in a rat model

Chiung-Kuei Huang,
Tunan Yu,
Suzanne M. de la Monte,
Jack R. Wands,
Zoltan Derdak,
Miran Kim

Published online: February 24, 2015

p191-198

EASL Recommendations on Treatment of Hepatitis C 2015

European Association for the Study of the Liver

Published online: April 21, 2015

p199-236

Open Access

EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis

European Association for the Study of the Liver,
Asociacion Latinoamericana para el Estudio del Higado

Published online: April 21, 2015

p237-264

Open Access

Machine perfusion in liver transplantation as a tool to prevent non-anastomotic biliary strictures: Rationale, current evidence and future directions

Pepijn D. Weeder,
Rianne van Rijn,
Robert J. Porte

Published online: March 11, 2015

p265-275

Open Access

No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver

Benjamin Herquel,

Céline Keime,
Irwin Davidson

Published online: February 19, 2015

p276-277

Open Access

Coagulation and fibrosis: A potential non-negligible target of statins in chronic hepatitis

Niccolò Bitto,
Francesco Salerno,

Armando Tripodi,

Vincenzo La Mura

Published online: February 25, 2015

p277-278

Open Access

Reply to: “Coagulation and fibrosis: A potential non-negligible target of statins in chronic hepatitis”

Tracey G. Simon,

Lindsay Y. King,
Raymond T. Chung

Published online: February 26, 2015

p279

Open Access

The problem of the most appropriate curative treatment for hepatocellular carcinoma. When to embolize? When to operate?

Francesco Guerra,

Giovanni Battista Levi Sandri

Published online: April 15, 2015

p280-281

Open Access

Reply to “The problem of the most appropriate curative treatment for hepatocellular carcinoma. When to embolize? When to operate?”

Beom Kyung Kim,
Seung Up Kim

Published online: April 13, 2015

p281-282

Open Access

Reduced mortality due to phlebotomy in moderately iron-loaded HFE haemochromatosis? The need for clinical trials

Martin B. Delatycki,

Lyle C. Gurrin,

Sim Yee Ong,

Grant A. Ramm,
Greg J. Anderson,

John K. Olynyk,

Katie J. Allen,

Amanda J. Nicoll,

Lawrie W. Powell

Published online: March 31, 2015

p282-283

Open Access

Reply to: “Reduced mortality due to phlebotomy in moderately iron-loaded HFE Haemochromatosis? The need for clinical trials”

Edouard Bardou-Jacquet,

Fabrice Lainé,

Yves Deugnier

Published online: April 01, 2015

p283-284

Open Access

Preservation injury of the distal extrahepatic bile duct of donor livers is representative for injury of the intrahepatic bile ducts

Negin Karimian,
Pepijn D. Weeder,
Fernanda Bomfati,
Annette S.H. Gouw,
Robert J. Porte

Published online: March 19, 2015

p284-287

Open Access

Hepatic encephalopathy treatment and its effect on driving abilities: A continental divide

Mette M. Lauridsen,

Jasmohan Singh Bajaj

Published online: March 19, 2015

p287-288

Open Access

Corrigendum to “Design and validation of a diagnostic score for biliary atresia” [J Hepatol 2014;61:116–123]

Mohamed Abdel-Salam El-Guindi,
Mostafa Mohamed Sira,
Ahmad Mohamed Sira,
Tahany Abdel-Hameed Salem,
Hatem Abdel-Sattar Konsowa,
Alif Abdel-Hakim Allam

Published online: May 07, 2015

p289

Corrigendum to “Diagnosis and management of acute kidney injury in patients with cirrhosis: Revised consensus recommendations of the International Club of Ascites” [J Hepatol 2015;62:968–974]

Paolo Angeli,
Pere Ginès,
Florence Wong,
...
W. Ray Kim,
Vicente Arroyo,
Guadalupe Garcia-Tsao

Published online: April 23, 2015

p290

Erratum to “The CLIF Consortium Acute Decompensation score (CLIF-C ADs) for prognosis of hospitalised cirrhotic patients without acute-on-chronic liver failure” [J Hepatol 2015;62:831–840]

Rajiv Jalan,
Marco Pavesi,
Faouzi Saliba,
...
Julia Wendon,
Mauro Bernardi,
Vicente Arroyo

Published online: April 30, 2015

p291

Erratum to “Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry” [J Hepatol 2015;62:541–548]

Liang-Tzung Lin,
Chueh-Yao Chung,
Wen-Chan Hsu,
...
D. Lorne J. Tyrrell,
Chun-Ching Lin,
Christopher D. Richardson

Published online: May 05, 2015

p292

July 2015

From the Editor's Desk

July 2015

Editorials

Research Articles

Viral Hepatitis

Cirrhosis

Transplantation

Liver Failure and Growth

Cancer

Molecular and Cell Biology

Genetic and Metabolic Diseases

Guidelines

Clinical Practice Guidelines

Review

Letters to the Editor

Corrigenda

Errata